The role of LEF1 in endometrial gland formation and carcinogenesis.

The role of LEF1 in endometrial gland formation and carcinogenesis.

Endometrial carcinoma is the most common gynecologic cancer, yet the mechanisms underlying this disease process are poorly understood. We hypothesized that Lef1 is required for endometrial gland formation within the uterus and is overexpressed in endometrial cancer. Using Lef1 knockout (KO) mice, we...

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Bibliographic Details
Main Authors: Dawne N Shelton, Hubert Fornalik, Traci Neff, Soo Yeun Park, David Bender, Koen DeGeest, Xiaoming Liu, Weiliang Xie, David K Meyerholz, John F Engelhardt, Michael J Goodheart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3391280?pdf=render

Internet

http://europepmc.org/articles/PMC3391280?pdf=render

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