Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation

Background. Cardiopulmonary bypass (CPB) causes systemic inflammatory response and ischemia-reperfusion (IR) injury. Objective. To investigate the effect and mechanism of simvastatin on myocardial injury in cardiac valve surgery with CPB. Methods. One hundred thirty patients were randomly assigned t...

Full description

Bibliographic Details
Main Authors:	Ping Hua, Jianyang Liu, Jun Tao, Rongjun Zou, Xifeng Lin, Dingwen Zhang, Songran Yang
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2017/6082430

Similar Items

Efficacy of Statin Therapy Related to Baseline Renal Function in Patients with Rheumatic Heart Disease Undergoing Cardiac Surgery
by: Rongjun Zou, et al.
Published: (2018-01-01)

Surgical myocardial revascularization without extracorporeal circulation
by: Salomón Soriano Ordinola Rojas, et al.
Published: (2003-05-01)

Neurocardiology: Cardiovascular Changes and Specific Brain Region Infarcts
by: Rongjun Zou, et al.
Published: (2017-01-01)

Analysis of Genes Involved in Persistent Atrial Fibrillation: Comparisons of ‘Trigger’ and ‘Substrate’ Differences
by: Rongjun Zou, et al.
Published: (2018-06-01)

Myocardial revascularization without extracorporeal circulation; Why hasn't it convinced yet?
by: Efstratios Apostolakis, et al.
Published: (2017-01-01)

Biatrial versus Isolated Left Atrial Ablation in Atrial Fibrillation: A Systematic Review and Meta-Analysis
by: Hongmu Li, et al.
Published: (2018-01-01)

Cytoflavin as an Additional Method for Myocardial Salvage During Operations Under Extracorporeal Circulation
by: Z. Z Nadiradze, et al.
Published: (2006-06-01)

Techniques of extracorporeal circulation.
by: Warshawski, Frances. G.
Published: (1958)

Dynamics of the circulation with reference to extracorporeal circulation
by: Scott, Peter
Published: (1963)

The role of neutrophils in destruction of vascular endothelium in myocardial revascularization surgeries under extracorporeal circulation
by: V. V. Novitsky, et al.
Published: (2005-12-01)

The Efficiency of Epidural Anesthesia and Postoperative Analgesia during Myocardial Revascularization without Extracorporeal Circulation
by: A. V. Yeremeyev, et al.
Published: (2010-12-01)

Revascularização do miocárdio sem circulação extracorpórea Myocardial revascularization without extracorporeal circulation
by: Enio Buffolo
Published: (2005-10-01)

The adrenal gland in extracorporeal circulation
by: Kuzela, Ladislav
Published: (1968)

Circulação Extracorpórea Extracorporeal circulation
by: Domingo M Braile
Published: (2010-12-01)

Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia
by: Irundika H.K. Dias, et al.
Published: (2018-06-01)

Inhaled Nitric Oxide for the Prevention of Impaired Arterial Oxygenation during Myocardial Revascularization with Extracorporeal Circulation
by: I. A. Kozlov, et al.
Published: (2011-02-01)

Extracorporeal Circulation Using an Extracorporeal Membrane Oxygenation System and an Autotransfusion System
by: Yu. A. Bakhareva, et al.
Published: (2010-02-01)

Analysis of the Use of Extracorporeal Circulation on the In-Hospital Outcomes of Dialytic Patients Who Underwent Myocardial Revascularization Surgery
by: Matheus Miranda, et al.

Pulmonary lobectomy in two multitrauma patients under extracorporeal circulation placed preoperatively in an intensive care unit: A case report
by: Clément Faidherbe, et al.
Published: (2019-07-01)

Nitric oxide : An ally in extracorporeal circulation?
by: Melki, Vilyam
Published: (2016)

Influence of ulinastatin on myocardial enzyme spectrum, inflammatory state and reperfusion injury of patients with extracorporeal circulation heart operation
by: Ming-Bin Deng, et al.
Published: (2016-05-01)

Efficacy of Extracorporeal Shockwave Therapy in Frozen Shoulder
by: Babak Vahdatpour, et al.
Published: (2014-01-01)

Bioinformatic gene analysis for potential biomarkers and therapeutic targets of atrial fibrillation-related stroke
by: Rongjun Zou, et al.
Published: (2019-02-01)

Extracorporeal photo-immunotherapy for circulating tumor cells.
by: Gwangseong Kim, et al.
Published: (2015-01-01)

Studies on Blood Viscosity During Extracorporeal Circulation
by: NAGASHIMA, HISASHI
Published: (1968)

Effects of extracorporeal circulation on free tissue transfers.
Published: (1989)

Enterohepatic circulation in hamsters with an extracorporeal bile duct.
by: M Fuchs, et al.
Published: (1992-09-01)

In silico study of the dynamic interaction between extracorporeal circulation and native circulation
by: Bongert Markus, et al.
Published: (2018-09-01)

Low-Level Light Therapy Protects Red Blood Cells Against Oxidative Stress and Hemolysis During Extracorporeal Circulation
by: Tomasz Walski, et al.
Published: (2018-05-01)

COMPARATIVE EFFICACY AND SAFETY OF HYPOLIPIDEMIC THERAPY WITH GENERIC AND ORIGINAL MEDICINAL PRODUCTS OF SIMVASTATIN
by: E. I. Tarlovskaya, et al.
Published: (2016-01-01)

Extracorporeal circulation-from cardiopulmonary bypass to extracorporeal membrane oxygenation and mechanical cardiac assist device therapy: A constant evolution
by: Harish Ramakrishna
Published: (2015-01-01)

Extracorporeal Circulation: Effect of Long-Term (24-Hour) Circulation on Blood Components
by: Solberg, Robert Glen
Published: (2014)

Long-Term Leukocyte Filtration Should Be Avoided during Extracorporeal Circulation
by: Jiali Tang, et al.
Published: (2013-01-01)

Surgical outcomes in cardiogenic shock patients with preoperative extracorporeal membrane oxygenation (ECMO)
by: Mahmoud Yousef Ibrahim Abuharb, et al.
Published: (2021-08-01)

The Influence of Preoperative Music on Patients Undergoing Extracorporeal Shock Wave Lithotripsy (ESWL)
by: Lee-Shuan, Lin, et al.
Published: (2003)

Preoperative endothelial dysfunction in cutaneous microcirculation is associated with postoperative organ injury after cardiac surgery using extracorporeal circulation: a prospective cohort study
by: Stanislas Abrard, et al.
Published: (2021-01-01)

Early Activation of Children Operated on under Extracorporeal Circulation
by: P. R. Dudov, et al.
Published: (2008-02-01)

Application and Prospect of Extracorporeal Circulation in General Thoracic Surgery
by: Haitao MA
Published: (2018-04-01)

Cerebral Perfusion and Metabolism during Experimental Extracorporeal Circulation
by: Jonsson, Ove
Published: (2011)

Clinical Study of the Cerebral Hemodynamics during Extracorporeal Circulation
by: KUBOTA, YASUKAZU
Published: (1968)