Membrane TNF confers protection to acute mycobacterial infection

Membrane TNF confers protection to acute mycobacterial infection

<p>Abstract</p> <p>Background</p> <p>Tumour necrosis factor (TNF) is crucial for the control of mycobacterial infection as TNF deficient (KO) die rapidly of uncontrolled infection with necrotic pneumonia. Here we investigated the role of membrane TNF for host resistance...

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Bibliographic Details
Main Authors: Yeremeev Vladimir, Grivennikov Sergei I, Dambuza Ivy, Allie Nasiema, Fremond Cecile, Quesniaux Valerie FJ, Jacobs Muazzam, Ryffel Bernhard
Format: Article
Language:English
Published: BMC 2005-11-01
Series:Respiratory Research
Subjects:
Mycobacterium tuberculosis H37Rv
membrane TNF
TNF-deficiency
T cell recruitment
granuloma
Online Access:http://respiratory-research.com/content/6/1/136

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