luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]

Light exposure has a profound impact on human physiology and behaviour. For example, light exposure at the wrong time can disrupt our circadian rhythms and acutely suppress the production of melatonin. In turn, appropriately timed light exposure can support circadian photoentrainment. Beginning with...

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Main Authors: Manuel Spitschan, James Mead, Chris Roos, Chris Lowis, Ben Griffiths, Paul Mucur, Michael Herf
Format: Article
Language:English
Published: Wellcome 2021-06-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/6-69/v2
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spelling doaj-f466482b25f6447d8d35e9ec8c714ee72021-06-08T09:58:23ZengWellcomeWellcome Open Research2398-502X2021-06-01610.12688/wellcomeopenres.16595.218715luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]Manuel Spitschan0James Mead1Chris Roos2Chris Lowis3Ben Griffiths4Paul Mucur5Michael Herf6Department of Experimental Psychology, University of Oxford, Oxford, UKGo Free Range Ltd., London, UKGo Free Range Ltd., London, UKGo Free Range Ltd., London, UKGo Free Range Ltd., London, UKGhost Cassette Ltd., London, UKf.lux software LLC, Los Angeles, USALight exposure has a profound impact on human physiology and behaviour. For example, light exposure at the wrong time can disrupt our circadian rhythms and acutely suppress the production of melatonin. In turn, appropriately timed light exposure can support circadian photoentrainment. Beginning with the discovery that melatonin production is acutely suppressed by bright light more than 40 years ago, understanding which aspects of light drive the 'non-visual' responses to light remains a highly active research area, with an important translational dimension and implications for "human-centric" or physiologically inspired architectural lighting design. In 2018, the International Commission on Illumination (CIE) standardised the spectral sensitivities for predicting the non-visual effects of a given spectrum of light with respect to the activation of the five photoreceptor classes in the human retina: the L, M and S cones, the rods, and the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). Here, we described a novel, lean, user-friendly, open-access and open-source platform for calculating quantities related to light. The platform, called luox, enables researchers and research users in chronobiology, sleep research and adjacent field to turn spectral measurements into reportable quantities. The luox code base, released under the GPL-3.0 License, is modular and therefore extendable to other spectrum-derived quantities. luox has been endorsed by the CIE following black-box validation.https://wellcomeopenresearch.org/articles/6-69/v2
collection DOAJ
language English
format Article
sources DOAJ
author Manuel Spitschan
James Mead
Chris Roos
Chris Lowis
Ben Griffiths
Paul Mucur
Michael Herf
spellingShingle Manuel Spitschan
James Mead
Chris Roos
Chris Lowis
Ben Griffiths
Paul Mucur
Michael Herf
luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
Wellcome Open Research
author_facet Manuel Spitschan
James Mead
Chris Roos
Chris Lowis
Ben Griffiths
Paul Mucur
Michael Herf
author_sort Manuel Spitschan
title luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
title_short luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
title_full luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
title_fullStr luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
title_full_unstemmed luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
title_sort luox: novel validated open-access and open-source web platform for calculating and sharing physiologically relevant quantities for light and lighting [version 2; peer review: 2 approved]
publisher Wellcome
series Wellcome Open Research
issn 2398-502X
publishDate 2021-06-01
description Light exposure has a profound impact on human physiology and behaviour. For example, light exposure at the wrong time can disrupt our circadian rhythms and acutely suppress the production of melatonin. In turn, appropriately timed light exposure can support circadian photoentrainment. Beginning with the discovery that melatonin production is acutely suppressed by bright light more than 40 years ago, understanding which aspects of light drive the 'non-visual' responses to light remains a highly active research area, with an important translational dimension and implications for "human-centric" or physiologically inspired architectural lighting design. In 2018, the International Commission on Illumination (CIE) standardised the spectral sensitivities for predicting the non-visual effects of a given spectrum of light with respect to the activation of the five photoreceptor classes in the human retina: the L, M and S cones, the rods, and the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). Here, we described a novel, lean, user-friendly, open-access and open-source platform for calculating quantities related to light. The platform, called luox, enables researchers and research users in chronobiology, sleep research and adjacent field to turn spectral measurements into reportable quantities. The luox code base, released under the GPL-3.0 License, is modular and therefore extendable to other spectrum-derived quantities. luox has been endorsed by the CIE following black-box validation.
url https://wellcomeopenresearch.org/articles/6-69/v2
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