P53, Bcl2 and Bax Expression and Apoptosis in Perifosine and Vitamin D-Treated Endometrial Cancer Cell Line (HEC1A)

Endometrial cancer is the most common cancer of the female reproductive system. Perifosine has shown anti-tumor activity in a variety of cancers by inhibition of AKT phosphorylation. The active metabolite of vitamin D (1,25(OH)2D3) has anti-proliferative and pro-apoptotic properties and is recognize...

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Bibliographic Details
Main Authors: Meryem İlkay Karagül, Savaş Aktaş, Derya Yetkin, Gülsen Bayrak, Didem Çelikcan
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Proceedings
Subjects:
P53
BAX
Online Access:https://www.mdpi.com/2504-3900/2/25/1564