CXCL2-mediated ATR/CHK1 signaling pathway and platinum resistance in epithelial ovarian cancer

CXCL2-mediated ATR/CHK1 signaling pathway and platinum resistance in epithelial ovarian cancer

Abstract Tumor microenvironment and chemokines play a significant role in cancer chemoresistance. This study was designed to reveal the important role of CXCL2 in platinum resistance in epithelial ovarian cancer (EOC). Differently expressed (DE) genes were screen out based on analysis of GSE114206 d...

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Bibliographic Details
Main Authors: Sipei Nie, Yicong Wan, Hui Wang, Jinhui Liu, Jing Yang, Rui Sun, Huangyang Meng, Xiaolin Ma, Yi Jiang, Wenjun Cheng
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian cancer (EOC)
Platinum-resistance
Chemokine
CXCL2
Online Access:https://doi.org/10.1186/s13048-021-00864-3

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