Urinary Iron Excretion is Associated with Urinary Full-Length Megalin and Renal Oxidative Stress in Chronic Kidney Disease

Urinary Iron Excretion is Associated with Urinary Full-Length Megalin and Renal Oxidative Stress in Chronic Kidney Disease

Background/Aims: Megalin mediates the uptake of glomerular-filtered iron in the proximal tubules. Urinary full length megalin (C-megalin) excretion has been found to be increased in association with megalin-mediated metabolic load to the endo-lysosomal system in proximal tubular epithelial cells (PT...

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Main Authors: Shinya Nakatani, Ayumi Nakatani, Eiji Ishimura, Norikazu Toi, Akihiro Tsuda, Katsuhito Mori, Masanori Emoto, Yoshiaki Hirayama, Akihiko Saito, Masaaki Inaba
Format: Article
Language:English
Published: Karger Publishers 2018-03-01
Series:Kidney & Blood Pressure Research
Subjects:
CKD
Oxidative stress
Urinary iron
Megalin
Online Access:https://www.karger.com/Article/FullText/488470

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https://www.karger.com/Article/FullText/488470

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