Serum urate and lung cancer: a cohort study and Mendelian randomization using UK Biobank

Serum urate and lung cancer: a cohort study and Mendelian randomization using UK Biobank

Abstract Background Serum urate is the most abundant small molecule with antioxidant properties found in blood and the epithelial lining fluid of the respiratory system. Moderately raised serum urate is associated with lower rates of lung cancer and COPD in smokers but whether these relationships re...

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Bibliographic Details
Main Authors: Laura J. Horsfall, Ian P. Hall, Irwin Nazareth
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Respiratory Research
Subjects:
Mendelian randomization
Urate
Lung function
Causal relationship
Lung cancer
Smoking phenotypes
Online Access:https://doi.org/10.1186/s12931-021-01768-y

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