SPARC Inhibits LPA-Mediated Mesothelial—Ovarian Cancer Cell Crosstalk

SPARC Inhibits LPA-Mediated Mesothelial—Ovarian Cancer Cell Crosstalk

The interplay between peritoneal mesothelial cells and ovarian cancer cells is critical for the initiation and peritoneal dissemination of, and ascites formation in, ovarian cancer. The production of lysophosphatidic acid (LPA) by both peritoneal mesothelial cells and ovarian cancer cells has been...

Full description

Bibliographic Details
Main Authors:	Neveen A. Said, Ida Najwer, Matthew J. Socha, David J. Fulton, Samuel C. Mok, Kouros Motamed
Format:	Article
Language:	English
Published:	Elsevier 2007-01-01
Series:	Neoplasia: An International Journal for Oncology Research
Subjects:	SPARC LPA IL-6 ovarian cancer mesothelial cells
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558607800133

Similar Items

Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells
by: Wang J, et al.
Published: (2018-12-01)

SPARC Inhibits Metabolic Plasticity in Ovarian Cancer
by: Christine Naczki, et al.
Published: (2018-10-01)

A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer
by: Martyna Pakuła, et al.
Published: (2019-05-01)

Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination
by: Watanabe Takafumi, et al.
Published: (2012-02-01)

Ascites from ovarian cancer patients stimulates MUC16 mucin expression and secretion in human peritoneal mesothelial cells through an Akt-dependent pathway
by: Isabelle Matte, et al.
Published: (2019-04-01)

Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion
by: Kaire Ojasalu, et al.
Published: (2020-09-01)

Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling Pathway
by: Jie Zhang, et al.
Published: (2020-02-01)

Blocking LPA-dependent signaling increases ovarian cancer cell death in response to chemotherapy
by: LeAnn C. Rogers, et al.
Published: (2018-05-01)

Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families
by: Sébastien Enault, et al.
Published: (2018-08-01)

Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination
by: Kazumasa Mogi, et al.
Published: (2021-03-01)

Effects of the LPA1 Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice
by: Sara Tabbai, et al.
Published: (2019-06-01)

Rôle de l’axe Autotaxine (ATX)- Acide Lysophosphatidique (LPA) et récepteur LPA1 dans la dissémination métastatique des cancers du sein
by: David, Marion
Published: (2010)

The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis
by: Angela Rynne-Vidal, et al.
Published: (2015-09-01)

Mesothelial cyst of epididymis - a rare presentation
by: Shubha N Rao, et al.
Published: (2002-01-01)

TNF-α promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines[S]
by: Chenqi Zhao, et al.
Published: (2011-07-01)

Descriptor-based Fitting of LPA3 Inhibitors into a Single Predictive Mathematical Model
by: Olaposi Idowu Omotuyi, et al.
Published: (2014-10-01)

Secreted protein acidic and rich in cysteine (SPARC) is associated with nasopharyngeal carcinoma metastasis and poor prognosis
by: Wang Hai-Yun, et al.
Published: (2012-02-01)

The Role of Inflammasomes in Asbestos-Induced Mesothelial to Fibroblastic Transition
by: Thompson, Joyce K.
Published: (2017)

Optimization of Fibrin Scaffolds to Study Friction in Cultured Mesothelial Cells
by: Bodega, F., et al.
Published: (2022)

SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation
by: Giallongo Cesarina, et al.
Published: (2013-02-01)

Da contestação à responsabilidade mútua: uma análise entre o LPA e a NEPAD
by: Anselmo Otavio
Published: (2017-03-01)

Differential effects of thymoquinone on lysophosphatidic acid-induced oncogenic pathways in ovarian cancer cells
by: Ji Hee Ha, et al.
Published: (2020-05-01)

Laparoscopic management of a rare tumor at an uncommon location: Porta hepatis mesothelial cyst
by: Raghavendra Havannavar, et al.
Published: (2015-01-01)

Primary papillary mesothelial hyperpla-sia of the renal capsule - an unusual cause of renal calcification
by: Sanjay P Kolte, et al.
Published: (2003-01-01)

A solid variant of splenic mesothelial cyst, a case report with molecular analysis
by: Ekin Guney, et al.
Published: (2021-06-01)

Implication de la protéine matricielle SPARC dans la dissémination métastatique des mélanomes cutanés
by: Tichet, Mélanie
Published: (2013)

SPARC Ameliorates Ovarian Cancer-Associated Inflammation
by: Neveen A. Said, et al.
Published: (2008-10-01)

Metalloproteinases in Ovarian Cancer
by: Preston Carey, et al.
Published: (2021-03-01)

From the Lago's plan of action (LPA) to the new partnership for Africa's development(NEPAD): The political economy of African regional initiatives
by: Ikome, Francis Nguendi
Published: (2006)

Aberrant Promoter Methylation of Sparc in Ovarian Cancer
by: Matthew J. Socha, et al.
Published: (2009-02-01)

Combined serum and immunohistochemical differentiation between reactive, and malignant mesothelial proliferations
by: Gehan F. Al mehy, et al.
Published: (2015-07-01)

3D laparoscopic partial splenectomy for large mesothelial cyst: a case report
by: SHI Xiaoju, et al.
Published: (2017-03-01)

Spatio-temporal expression profile of matrix metalloproteinase (Mmp) modulators Reck and Sparc during the rat ovarian dynamics
by: Gabriel Levin, et al.
Published: (2018-11-01)

Peritoneal simple mesothelial cyst: a case report
by: Yu. V. Popov, et al.
Published: (2019-09-01)

Low Levels of SPARC are Associated with Tumor Progression and Poor Prognosis in Human Endometrial Carcinoma
by: Wang L, et al.
Published: (2020-11-01)

SPARC is Required in the Drosophila melanogaster Fat Body for ECM Homeostasis during Larval Development
by: Baratta, Cristina
Published: (2012)

Risk Factors for High Mesothelial Cell Counts in HIV-negative Patients With Tuberculous Pleural Effusion
by: Shih-Lung Cheng, et al.
Published: (2010-06-01)

Unusual giant multilocular mesothelial cyst of mediastinum
by: Takehiko Manabe, et al.
Published: (2020-10-01)

Albumin-Modified Melanin-Silica Hybrid Nanoparticles Target Breast Cancer Cells via a SPARC-Dependent Mechanism
by: Gennaro Sanità, et al.
Published: (2020-07-01)

Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis
by: Chen Jie, et al.
Published: (2012-10-01)