Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

<p>Abstract</p> <p>Background</p> <p>Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many inflammation associated genes. In this paper we examine whether the signal from T...

Full description

Bibliographic Details
Main Authors: Ozinsky Adrian O, Sweet Matthew J, Underhill David M, Hume David A, Liew Foo Y, Aderem Alan
Format: Article
Language:English
Published: BMC 2001-10-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/2/11

Similar Items

Similar Items