IgM and IgG against Plasmodium falciparum lysate as surrogates of malaria exposure and protection during pregnancy

IgM and IgG against Plasmodium falciparum lysate as surrogates of malaria exposure and protection during pregnancy

Abstract Background Difficulties to disentangle the protective versus exposure role of anti-malarial antibodies hamper the identification of clinically-relevant immune targets. Here, factors affecting maternal IgG and IgMs against Plasmodium falciparum antigens, as well as their relationship with pa...

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Bibliographic Details
Main Authors: Alfredo Mayor, Carlota Dobaño, Augusto Nhabomba, Caterina Guinovart, Alfons Jiménez, Maria Nelia Manaca, Ruth Aguilar, Arnoldo Barbosa, Mauricio H. Rodríguez, Pau Cisteró, Lazaro M. Quimice, Clara Menéndez, John J. Aponte, Jaume Ordi, Chetan E. Chitnis, Pedro L. Alonso
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Malaria Journal
Subjects:
Malaria
Pregnancy
Heterogeneity
Antibody
Immunity
Online Access:http://link.springer.com/article/10.1186/s12936-018-2331-4

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