Cryptococcus laurentii fungaemia in a cervical cancer patient

Infections caused by emerging Cryptococcus non-neoformans species are being reported with increasingly frequency. Here, we present a case of fungaemia by Cryptococcus laurentii in a woman receiving aggressive immunosuppressive therapy for cervical neoplasia. Three venous blood samples were aseptical...

Full description

Bibliographic Details
Main Authors: Rejane Pereira Neves, Reginaldo Gonçalves de Lima Neto, Melyna Chaves Leite, Vanessa Karina Alves da Silva, Franz de Assis Graciano dos Santos, Danielle Patrícia Cerqueira Macêdo
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S141386701500149X
id doaj-f3ffb7b2ff2444ba8571927b70d85259
record_format Article
spelling doaj-f3ffb7b2ff2444ba8571927b70d852592020-11-25T01:29:40ZengElsevierBrazilian Journal of Infectious Diseases1413-86702015-11-01196660663S1413-86702015000600660Cryptococcus laurentii fungaemia in a cervical cancer patientRejane Pereira Neves0Reginaldo Gonçalves de Lima Neto1Melyna Chaves Leite2Vanessa Karina Alves da Silva3Franz de Assis Graciano dos Santos4Danielle Patrícia Cerqueira Macêdo5Departamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, BrazilDepartamento de Medicina Tropical, Universidade Federal de Pernambuco (UFPE), Recife, PE, BrazilDepartamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, BrazilDepartamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, BrazilDepartamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, BrazilDepartamento de Ciências Farmacêuticas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil; Corresponding author at: Universidade Federal de Pernambuco, Av. Avenida Professor Nelson Chaves, s/n, Cidade Universitária, 50670-420 Recife, PE, Brazil.Infections caused by emerging Cryptococcus non-neoformans species are being reported with increasingly frequency. Here, we present a case of fungaemia by Cryptococcus laurentii in a woman receiving aggressive immunosuppressive therapy for cervical neoplasia. Three venous blood samples were aseptically collected on consecutive days and C. laurentii was isolated and identified through phenotypic and molecular methods. After central venous catheter removal and appropriate antifungal therapy, the patient showed significant improvement and blood culture became negative. Thus, patients following immunosuppressive therapies and using invasive medical devices are at risk of C. laurentii blood infections. Keywords: Cryptococcus laurentii, Fungaemia, Cancerhttp://www.sciencedirect.com/science/article/pii/S141386701500149X
collection DOAJ
language English
format Article
sources DOAJ
author Rejane Pereira Neves
Reginaldo Gonçalves de Lima Neto
Melyna Chaves Leite
Vanessa Karina Alves da Silva
Franz de Assis Graciano dos Santos
Danielle Patrícia Cerqueira Macêdo
spellingShingle Rejane Pereira Neves
Reginaldo Gonçalves de Lima Neto
Melyna Chaves Leite
Vanessa Karina Alves da Silva
Franz de Assis Graciano dos Santos
Danielle Patrícia Cerqueira Macêdo
Cryptococcus laurentii fungaemia in a cervical cancer patient
Brazilian Journal of Infectious Diseases
author_facet Rejane Pereira Neves
Reginaldo Gonçalves de Lima Neto
Melyna Chaves Leite
Vanessa Karina Alves da Silva
Franz de Assis Graciano dos Santos
Danielle Patrícia Cerqueira Macêdo
author_sort Rejane Pereira Neves
title Cryptococcus laurentii fungaemia in a cervical cancer patient
title_short Cryptococcus laurentii fungaemia in a cervical cancer patient
title_full Cryptococcus laurentii fungaemia in a cervical cancer patient
title_fullStr Cryptococcus laurentii fungaemia in a cervical cancer patient
title_full_unstemmed Cryptococcus laurentii fungaemia in a cervical cancer patient
title_sort cryptococcus laurentii fungaemia in a cervical cancer patient
publisher Elsevier
series Brazilian Journal of Infectious Diseases
issn 1413-8670
publishDate 2015-11-01
description Infections caused by emerging Cryptococcus non-neoformans species are being reported with increasingly frequency. Here, we present a case of fungaemia by Cryptococcus laurentii in a woman receiving aggressive immunosuppressive therapy for cervical neoplasia. Three venous blood samples were aseptically collected on consecutive days and C. laurentii was isolated and identified through phenotypic and molecular methods. After central venous catheter removal and appropriate antifungal therapy, the patient showed significant improvement and blood culture became negative. Thus, patients following immunosuppressive therapies and using invasive medical devices are at risk of C. laurentii blood infections. Keywords: Cryptococcus laurentii, Fungaemia, Cancer
url http://www.sciencedirect.com/science/article/pii/S141386701500149X
work_keys_str_mv AT rejanepereiraneves cryptococcuslaurentiifungaemiainacervicalcancerpatient
AT reginaldogoncalvesdelimaneto cryptococcuslaurentiifungaemiainacervicalcancerpatient
AT melynachavesleite cryptococcuslaurentiifungaemiainacervicalcancerpatient
AT vanessakarinaalvesdasilva cryptococcuslaurentiifungaemiainacervicalcancerpatient
AT franzdeassisgracianodossantos cryptococcuslaurentiifungaemiainacervicalcancerpatient
AT daniellepatriciacerqueiramacedo cryptococcuslaurentiifungaemiainacervicalcancerpatient
_version_ 1725095590151323648