Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication

Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication

Ebulin l is an A-B toxin, and despite the presence of a B chain, this toxin displays much less toxicity to cells than the potent A-B toxin ricin. Here, we studied the binding, mechanisms of endocytosis, and intracellular pathway followed by ebulin l and compared it with ricin. COS-1 cells and HeLa c...

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Bibliographic Details
Main Authors: Rosario Iglesias, José M. Ferreras, Alicia Llorente, Lucía Citores
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Toxins
Subjects:
apoptosis
clathrin
dynamin
ebulin
endocytosis
intracellular transport
Online Access:https://www.mdpi.com/2072-6651/13/2/102

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