Interleukin-26 is overexpressed in human sepsis and contributes to inflammation, organ injury, and mortality in murine sepsis

Interleukin-26 is overexpressed in human sepsis and contributes to inflammation, organ injury, and mortality in murine sepsis

Abstract Background Sepsis is a serious syndrome that is caused by an unbalanced host inflammatory response to an infection. The cytokine network plays a pivotal role in the orchestration of inflammatory response during sepsis. IL-26 is an emerging proinflammatory member of the IL-10 cytokine family...

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Bibliographic Details
Main Authors: Hongmei Tu, Xiaofei Lai, Jiaxi Li, Lili Huang, Yi Liu, Ju Cao
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Critical Care
Subjects:
Sepsis
Inflammation
IL-26
Neutrophils
Mortality
Online Access:http://link.springer.com/article/10.1186/s13054-019-2574-7

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