Modelling of L-valine Repeated Fed-batch Fermentation Process Taking into Account the Dissolved Oxygen Tension

This article deals with synthesis of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-valine production. The presented approach of the investigation includes the following main procedures: description of the process by generalized stoichiome...

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Bibliographic Details
Main Authors: Tzanko Georgiev, Ignat Dimov, Kalin Todorov, Julia Kristeva, Alexander Ratkov
Format: Article
Language:English
Published: Academic Publishing House 2009-03-01
Series:Bioautomation
Subjects:
Online Access:http://www.clbme.bas.bg/bioautomation/2009/vol_12.1/files/12_1.4.pdf
Description
Summary:This article deals with synthesis of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-valine production. The presented approach of the investigation includes the following main procedures: description of the process by generalized stoichiometric equations; preliminary data processing and calculation of specific rates for main kinetic variables; identification of the specific rates takes into account the dissolved oxygen tension; establishment and optimisation of dynamic model of the process; simulation researches. MATLAB is used as a research environment.
ISSN:1313-261X
1312-451X