Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response

The endoplasmic reticulum (ER) is the site of folding of membrane and secreted proteins in the cell. Physiological or pathological processes that disturb protein folding in the endoplasmic reticulum cause ER stress and activate a set of signaling pathways termed the Unfolded Protein Response (UPR)....

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Bibliographic Details
Main Authors: Afshin Samali, Una FitzGerald, Shane Deegan, Sanjeev Gupta
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2010/830307

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