Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC<sup>®</sup> Natural Adjuvant against Aspergillosis

Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC<sup>®</sup> Natural Adjuvant against Aspergillosis

Invasive pulmonary aspergillosis represents one of the most serious fungal infections among immunocompromised patients. In this study, we aimed to analyze the in vivo efficacy of prophylactic oral amphotericin B (AMB) encapsulated in modified chitosan-nanoparticles (Nanomerics’ Molecular E...

Full description

Bibliographic Details
Main Authors:	Alba Pérez-Cantero, Dolores R. Serrano, Patricia Navarro-Rodríguez, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Juan J. Torrado, Javier Capilla
Format:	Article
Language:	English
Published:	MDPI AG 2019-09-01
Series:	Pharmaceutics
Subjects:	aspergillosis amphotericin B oral delivery chitosan shiitake <i>Lentinula edodes</i> AHCC<sup>®</sup> Molecular Envelope Technology
Online Access:	https://www.mdpi.com/1999-4923/11/9/456

Similar Items

Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of <i>Bifidobacterium longum</i>, AHCC<sup>®</sup> and Azithromycin in Healthy Individuals
by: Abeed H. Chowdhury, et al.
Published: (2019-10-01)

ANTIBACTERIAL ACTIVITY OF LENTINULA EDODES GROWN IN LIQUID MEDIUM Atividade antibacteriana de Lentinula edodes cultivado em meio líquido
by: Noemia Kazue Ishikawa, et al.
Published: (2001-10-01)

Dermatite flagelada ao shiitake
by: Thatiana Catunda Torres Mota, et al.
Published: (2017-04-01)

Cam Kavanozda Yetiştirilen Shiitake (Lentinula edodes) Mantarının Bazı Morfolojik Özellikleri ve Antibakteriyel Performansı
by: Elif Ayşe ERDOĞAN ELİUZ
Published: (2019-04-01)

Avaliação nutricional do cogumelo shiitake [Lentinula edodes (Berk.) Pegler] em função da linhagem e do tipo de eucalipto cultivado Nutritional evaluation of shiitake mushroom [(Lentinula edodes (Berk.) Pegler] in function of the strain and type of cultivated eucalyptus
by: Meire Cristina Nogueira de Andrade, et al.
Published: (2008-12-01)

Digital monitoring of mycelium growth kinetics and vigor of shiitake (Lentinula edodes (Berk.) Pegler) on agar medium Monitoramento digital do crescimento e vigor do shiitake (Lentinula edodes (Berk.) Pegler) em meio de cultura
by: Renato Mamede de Castro Montini, et al.
Published: (2006-03-01)

Growth evaluation of Lentinula edodes in solid medium cultures for mycelium production as inoculum
by: Villegas E Valeska, et al.
Published: (2007-12-01)

Attenuating the rate of total body fat accumulation and alleviating liver damage by oral administration of vitamin D-enriched edible mushrooms in a diet-induced obesity murine model is mediated by an anti-inflammatory paradigm shift
by: A. Drori, et al.
Published: (2017-11-01)

Antimutagenic action of Lentinula edodes and Agaricus blazei on Aspergillus nidulans conidia Ação antimutagênica de Lentinula edodes e Agaricus blazei em conídios de Aspergillus nidulans
by: Edneia A. Souza-Paccola, et al.
Published: (2004-12-01)

Thermal and mechanical shocks affecting the first flush of production of Lentinula edodes on Eucalyptus saligna logs Coque térmico e mecânico afetando o primeiro fluxo de produção de Lentinila edodes em toras de Eucalyptus saligna
by: Humberto Franco Shiomi, et al.
Published: (2007-06-01)

Pathological Properties of Cryptococcus pseudolongus on the Mycelia and Fruit Body of Lentinula edodes
by: Hyuk Woo Kwon, et al.
Published: (2021-03-01)

Evaluación de la producción del hongo Lentinula edodes Pegler en bloques sintéticos a base de residuos agroindustriales
by: Valeska Villegas Escobar, et al.
Published: (2007-12-01)

Processamento mínimo de cogumelos shiitake (Lentinula edodes)
by: Santana, Cristiane de Castro
Published: (2017)

Avaliação do crescimento micelial de linhagens de shiitake, da produção em toras de eucalipto e de alterações físicas da madeira = Evaluation of mycelium growth of shiitake strains, of production in Eucalyptus logs and of physical alteration of the wood
by: Elias Taylor Durgante Severo, et al.
Published: (2007-01-01)

The Effect of Different Agricultural Wastes on Aroma Composition of Shiitake (Lentinula edodes (Berk.) Pegler) Mushroom
by: Gökhan Baktemur, et al.
Published: (2020-08-01)

Obtenção e avaliação de linhagens híbridas e desenvolvimento dos processos de inóculos líquidos para cultivo axênico de lentinula edodes (berk.) pegler
by: Pereira, Diego Melo
Published: (2015)

Obtenção e avaliação de linhagens híbridas e desenvolvimento dos processos de inóculos líquidos para cultivo axênico de lentinula edodes (berk.) pegler
by: Pereira, Diego Melo
Published: (2015)

Obtenção e avaliação de linhagens híbridas e desenvolvimento dos processos de inóculos líquidos para cultivo axênico de lentinula edodes (berk.) pegler
by: Pereira, Diego Melo
Published: (2015)

Proteome Analysis and In Vitro Antiviral, Anticancer and Antioxidant Capacities of the Aqueous Extracts of <i>Lentinula edodes</i> and <i>Pleurotus ostreatus</i> Edible Mushrooms
by: Shaza M. Elhusseiny, et al.
Published: (2021-07-01)

Theoretical and experimental substantiation of a fungal therapeutic drug with immunomodulating and antitumor action according to the authors’ prescription
by: V. A. Кuchmistov, et al.
Published: (2018-02-01)

Resíduo de colheita de shiitake (Lentinula edodes (Berk.) Pegler) na alimentação de frangos de corte e poedeiras comerciais
by: Ferreira Netto, Raimundo Gonçalves
Published: (2018)

Atividade biológica de Lentinula edodes e produção de shiitake em substrato enriquecido com selênio
by: Nunes, Regiane Gonçalves Feitosa Leal
Published: (2017)

<em>H</em>-Umbilical Lagrangian Submanifolds of the Nearly Kähler S<sup>3</sup> × S<sup>3</sup>
by: Miroslava Antić, et al.
Published: (2020-08-01)

Spinach Plants Favor the Absorption of K<sup>+</sup> over Na<sup>+</sup> Regardless of Salinity, and May Benefit from Na<sup>+</sup> When K<sup>+</sup> is Deficient in the Soil
by: Jorge F. S. Ferreira, et al.
Published: (2020-04-01)

Nucleotides and AHCC Enhance Th1 Responses In Vitro in <i>Leishmania</i>-Stimulated/Infected Murine Cells
by: María Auxiliadora Dea-Ayuela, et al.
Published: (2020-08-01)

Influence of <i>Clear<sup>T</sup></i> and<i> Clear<sup>T2</sup></i> Agitation Conditions in the Fluorescence Imaging of 3D Spheroids
by: Daniel N. Silva, et al.
Published: (2021-12-01)

Evaluación del crecimiento de Lentinula edodes en medios de cultivo sólidos para la producción de micelio como inóculo
by: Valeska Villegas E, et al.
Published: (2007-07-01)

Associated Charmonium-Bottomonium Production in a Single Boson <i>e</i><sup>+</sup><i>e</i><sup>−</sup> Annihilation
by: Ilia Belov, et al.
Published: (2021-07-01)

Protection and Safety Evaluation of Live Constructions Derived from the Pgm<sup>−</sup> and pPCP1<sup>−</sup> <i>Yersinia pestis</i> Strain
by: Xiuran Wang, et al.
Published: (2020-02-01)

Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na<sup>+</sup> and K<sup>+</sup> Currents
by: Ping-Chung Kuo, et al.
Published: (2020-07-01)

Topical Amphotericin B Semisolid Dosage Form for Cutaneous Leishmaniasis: Physicochemical Characterization, Ex Vivo Skin Permeation and Biological Activity
by: Diana Berenguer, et al.
Published: (2020-02-01)

Phase I and II Clinical Trial Comparing the LBSap, Leishmune<sup>®</sup>, and Leish-Tec<sup>®</sup> Vaccines against Canine Visceral Leishmaniasis
by: Rodrigo Dian de Oliveira Aguiar-Soares, et al.
Published: (2020-11-01)

NH<sub>4</sub><sup>+</sup> Toxicity, Which Is Mainly Determined by the High NH<sub>4</sub><sup>+</sup>/K<sup>+</sup> Ratio, Is Alleviated by CIPK23 in <i>Arabidopsis</i>
by: Sujuan Shi, et al.
Published: (2020-04-01)

<i>GhNHX3D</i>, A Vacuolar-Localized Na<sup>+</sup>/H<sup>+</sup> Antiporter, Positively Regulates Salt Response in Upland Cotton
by: Junping Feng, et al.
Published: (2021-04-01)

Analysis of <sup>15</sup>N-NO<sub>3</sub><sup>−</sup> Via Anoxic Slurries Coupled to MIMS Analysis: An Application to Estimate Nitrification by Burrowing Macrofauna
by: Paula Carpintero Moraes, et al.
Published: (2019-11-01)

Homomorphism-derivation functional inequalities in <em>C</em><sup>*</sup>-algebras
by: Choonkil Park, et al.
Published: (2020-06-01)

Structural Insights to the Heterotetrameric Interaction between the <i>Vibrio parahaemolyticus</i> PirA<i><sup>vp</sup></i> and PirB<i><sup>vp</sup></i> Toxins and Activation of the Cry-Like Pore-Forming Domain
by: Shin-Jen Lin, et al.
Published: (2019-04-01)

Global Landscapes of the <i>Na<sup>+</sup>/H<sup>+</sup> Antiporter (NHX)</i> Family Members Uncover their Potential Roles in Regulating the Rapeseed Resistance to Salt Stress
by: Jia-qian Cui, et al.
Published: (2020-05-01)

Nonsense Mutations in the Yeast <i>SUP35</i> Gene Affect the [<i>PSI<sup>+</sup></i>] Prion Propagation
by: Nina P. Trubitsina, et al.
Published: (2020-02-01)

Ethyl Acetate Fraction of Aqueous Extract of <i>Lentinula edodes</i> Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression
by: Hyerim Lee, et al.
Published: (2020-02-01)