Synthesis of New 2,5-Di-substituted 1,3,4-Oxadiazoles Bearing 2,6-Di-tert-butylphenol Moieties and Evaluation of Their Antioxidant Activity

Synthesis of New 2,5-Di-substituted 1,3,4-Oxadiazoles Bearing 2,6-Di-tert-butylphenol Moieties and Evaluation of Their Antioxidant Activity

Eleven new 2,6-di-tert-butyl-4-(5-aryl-1,3,4-oxadiazol-2-yl)phenols 5a–k were synthesized by reacting aryl hydrazides with 3,5-di-tert butyl 4-hydroxybenzoic acid in the presence of phosphorus oxychloride. The resulting compounds were characterized based on their IR, 1H-NMR, 13C-NMR, and HRMS data....

Full description

Bibliographic Details
Main Authors: Raied M. Shakir, Azhar Ariffin, Mahmood Ameen Abdulla
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Molecules
Subjects:
2,6-di-tert-butylphenol
hindered phenol
antioxidant
1,3,4-oxadiazole
FRAP
DPPH
Online Access:http://www.mdpi.com/1420-3049/19/3/3436

Similar Items

Similar Items