5-Methylcytosine and 5-Hydroxymethylcytosine Signatures Underlying Pediatric Cancers

In addition to the genetic variations, recent evidence has shown that DNA methylation of both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) underlies the pathogenesis of pediatric cancer. Given the high mortality rate, there is an urgent need to study the mechanisms contributing to the p...

Full description

Bibliographic Details
Main Authors: Shalu Jhanwar, Ajinkya Deogade
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Epigenomes
Subjects:
5mC
Online Access:https://www.mdpi.com/2075-4655/3/2/9