Autophagy Induced by Palmitic Acid Regulates Neutrophil Adhesion Through the Granule-Dependent Degradation of αMβ2 Integrin in Dairy Cows With Fatty Liver

β2 integrins are critical for neutrophil firm adhesion, trans-endothelial migration, and the recruitment to the inflamed tissue. Autophagy is implicated in cell migration and tumor metastasis through facilitating the turnover of β1 integrins; however, whether autophagy is able to control neutrophil...

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Bibliographic Details
Main Authors: Zhicheng Peng, Chenxu Zhao, Xiliang Du, Yuchen Yang, Yunfei Li, Yuxiang Song, Baochen Fang, Yuming Zhang, Xia Qin, Yuanyuan Zhang, Xiaobing Li, Zhe Wang, Xinwei Li, Guowen Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.726829/full