Reduced intestinal tumorigenesis in APCmin mice lacking melanin-concentrating hormone.

Reduced intestinal tumorigenesis in APCmin mice lacking melanin-concentrating hormone.

Melanin-concentrating hormone (MCH) is an evolutionary conserved hypothalamic neuropeptide that in mammals primarily regulates appetite and energy balance. We have recently identified a novel role for MCH in intestinal inflammation by demonstrating attenuated experimental colitis in MCH deficient mi...

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Bibliographic Details
Main Authors:	Jutta M Nagel, Brenda M Geiger, Apostolos K A Karagiannis, Beatriz Gras-Miralles, David Horst, Robert M Najarian, Dimitrios C Ziogas, Xinhua Chen, Efi Kokkotou
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3407051?pdf=render

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