Acquisition of cancer stem cell properties in osteosarcoma cells by defined factors

Acquisition of cancer stem cell properties in osteosarcoma cells by defined factors

Abstract Background Cancer stem cells (CSCs) are considered to be responsible for tumor initiation, formation, and poor prognosis of cancer patients. However, the rarity of CSCs in clinical samples makes it difficult to elucidate characteristics of CSCs, especially in osteosarcoma (OS). The aim of t...

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Bibliographic Details
Main Authors: Shuichi Fujiwara, Teruya Kawamoto, Yohei Kawakami, Yasufumi Koterazawa, Hitomi Hara, Toshiyuki Takemori, Kazumichi Kitayama, Shunsuke Yahiro, Kenichiro Kakutani, Tomoyuki Matsumoto, Takehiko Matsushita, Takahiro Niikura, Michiyo Koyanagi-Aoi, Takashi Aoi, Ryosuke Kuroda, Toshihiro Akisue
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Stem Cell Research & Therapy
Subjects:
Cancer stem cells
Chemoresistance
Osteosarcoma
Sarcosphere
Tumorigenicity
Online Access:http://link.springer.com/article/10.1186/s13287-020-01944-9

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http://link.springer.com/article/10.1186/s13287-020-01944-9

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