Coexistent retinal vasculitis and aggressive posterior retinopathy of prematurity in a preterm infant

• Main Authors: Sucheta R Kulkarni, Nikhil A Labshetwar, Nilesh A Kakade, Valvi T Chhaya
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2016-01-01
• Series: Journal of Clinical Ophthalmology and Research
• Subjects: Aggressive posterior retinopathy of prematurity; fungal sepsis; retinal vasculitis
• Online Access: http://www.jcor.in/article.asp?issn=2320-3897;year=2016;volume=4;issue=2;spage=100;epage=102;aulast=Kulkarni

We report a rare case with simultaneous occurrence of retinal vasculitis and aggressive posterior retinopathy of prematurity (APROP) in a preterm infant. During ROP screening at 5 weeks of age, RetCam imaging revealed early vascular shunts in zone I and plus disease diagnostic of APROP along with bilateral retinal vasculitis. APROP regressed with laser followed by intravitreal bevacizumab (IVB) in right eye and with laser only in left eye. Antifungal treatment was started (Fluconazole 6 mg/kg/day) on clinical suspicion of fungal sepsis with eventual resolution of retinal vasculitis. Retinal vasculitis can be an ocular sign of systemic fungal infection and can predispose an infant for development of retinopathy of prematurity (ROP). Simultaneous occurrence of both entities might pose a challenge in the management.