Performance of objective functions and optimisation procedures for parameter estimation in system biology models

Systems biology: Performance of parameter estimation procedures A systematic comparison of critical choices for faithful parameter-estimation identifies a combination of a hybrid optimisation algorithm (GLSDC) with data-driven normalisation of simulations (DNS) as the generally best option. Experime...

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Bibliographic Details
Main Authors: Andrea Degasperi, Dirk Fey, Boris N. Kholodenko
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-017-0023-2

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