Regulation of DNA Double-Strand Break Repair by Non-Coding RNAs

Regulation of DNA Double-Strand Break Repair by Non-Coding RNAs

DNA double-strand breaks (DSBs) are deleterious lesions that are generated in response to ionizing radiation or replication fork collapse that can lead to genomic instability and cancer. Eukaryotes have evolved two major pathways, namely homologous recombination (HR) and non-homologous end joining (...

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Bibliographic Details
Main Author:	Roopa Thapar
Format:	Article
Language:	English
Published:	MDPI AG 2018-10-01
Series:	Molecules
Subjects:	DNA repair long non-coding RNA microRNA DNA damage double-strand breaks NHEJ HR
Online Access:	https://www.mdpi.com/1420-3049/23/11/2789

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