Oxidative stress affects retinal pigment epithelial cell survival through epidermal growth factor receptor/AKT signaling pathway

AIM: To investigate the cross-talk between oxidative stress and the epidermal growth factor receptor (EGFR)/AKT signaling pathway in retinal pigment epithelial (RPE) cells. METHODS: Human RPE cell lines (ARPE-19 cell) were treated with different doses of epidermal growth factor (EGF) and hydrogen p...

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Bibliographic Details
Main Authors: Xiao-Dong Chen, Ming-Yang Su, Tao-Tao Chen, Hai-Yan Hong, Ai-Dong Han, Wen-Sheng Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-04-01
Series:International Journal of Ophthalmology
Subjects:
514
AKT
Online Access:http://www.ijo.cn/en_publish/2017/4/20170402.pdf