Molecules and mechanisms implicated in the peculiar antigenic activation process of human Vγ9Vδ2 T cells

In humans, as well as in most non-human primates, the major peripheral γδ T cell subset, which accounts several percent of the whole lymphoid cells pool in adults, carries an heterodimeric TCR composed of Vγ9 and Vδ2 chains. Vγ9Vδ2 T cells are specifically and strongly activated by small organic pyr...

Full description

Bibliographic Details
Main Authors: Christelle eHarly, Cassie-Marie ePeigné, Emmanuel eScotet
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00657/full