Long non-coding RNA LINC00485 acts as a microRNA-195 sponge to regulate the chemotherapy sensitivity of lung adenocarcinoma cells to cisplatin by regulating CHEK1

Long non-coding RNA LINC00485 acts as a microRNA-195 sponge to regulate the chemotherapy sensitivity of lung adenocarcinoma cells to cisplatin by regulating CHEK1

Abstract Background Long non-coding RNAs (lncRNAs) are a family of non-protein-coding RNAs, which have the ability to influence the chemo-resistance of lung adenocarcinoma (LAC). In this study, we explored the mechanism by which LINC00485 competitively binds to microRNA-195 (miR-195) in the regulati...

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Bibliographic Details
Main Authors: Wei Zuo, Wei Zhang, Fei Xu, Jing Zhou, Wei Bai
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Cancer Cell International
Subjects:
Long intervening non-coding RNA LINC00485
MicroRNA-195
CHEK1
Lung adenocarcinoma
Competitive endogenous RNA
Cisplatin
Online Access:http://link.springer.com/article/10.1186/s12935-019-0934-7

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