Preparation of labeled alkyl acyl glycerophosphorylcholine

A method for the preparation of 1-alkyl 2-acyl glycero-3-phosphorylcholine, labeled in the 2-position with oleic acid-1-14C is described. This method, based on the acylation of a 1-alkyl glycero-3-phosphorylcholine-CdCl2 complex which is, in turn, formed from 1-alk-1-enyl glycero-3-phosphorylcholine...

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Main Author:	A. POULOS
Format:	Article
Language:	English
Published:	Elsevier 1970-09-01
Series:	Journal of Lipid Research
Subjects:	phosphatidalcholine 1-alkyl 3-glycero-3-phosphorylcholine-CdCl2 complex acylation saturated ether phospholipid lecithinase C hydrolysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520429608

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spelling	doaj-f37d856c6ec6477e8ce0fcf36625f55d2021-04-24T05:54:50ZengElsevierJournal of Lipid Research0022-22751970-09-01115496498Preparation of labeled alkyl acyl glycerophosphorylcholineA. POULOS0Department of Chemical Pathology, The National Hospital, Queen Square, London, EnglandA method for the preparation of 1-alkyl 2-acyl glycero-3-phosphorylcholine, labeled in the 2-position with oleic acid-1-14C is described. This method, based on the acylation of a 1-alkyl glycero-3-phosphorylcholine-CdCl2 complex which is, in turn, formed from 1-alk-1-enyl glycero-3-phosphorylcholine by hydrogenation and subsequent reaction with cadmium chloride, offers a relatively simple means of preparing a labeled saturated ether phospholipid suitable for use in metabolic studies.http://www.sciencedirect.com/science/article/pii/S0022227520429608phosphatidalcholine1-alkyl 3-glycero-3-phosphorylcholine-CdCl2 complexacylationsaturated ether phospholipidlecithinase C hydrolysis
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	A. POULOS
spellingShingle	A. POULOS Preparation of labeled alkyl acyl glycerophosphorylcholine Journal of Lipid Research phosphatidalcholine 1-alkyl 3-glycero-3-phosphorylcholine-CdCl2 complex acylation saturated ether phospholipid lecithinase C hydrolysis
author_facet	A. POULOS
author_sort	A. POULOS
title	Preparation of labeled alkyl acyl glycerophosphorylcholine
title_short	Preparation of labeled alkyl acyl glycerophosphorylcholine
title_full	Preparation of labeled alkyl acyl glycerophosphorylcholine
title_fullStr	Preparation of labeled alkyl acyl glycerophosphorylcholine
title_full_unstemmed	Preparation of labeled alkyl acyl glycerophosphorylcholine
title_sort	preparation of labeled alkyl acyl glycerophosphorylcholine
publisher	Elsevier
series	Journal of Lipid Research
issn	0022-2275
publishDate	1970-09-01
description	A method for the preparation of 1-alkyl 2-acyl glycero-3-phosphorylcholine, labeled in the 2-position with oleic acid-1-14C is described. This method, based on the acylation of a 1-alkyl glycero-3-phosphorylcholine-CdCl2 complex which is, in turn, formed from 1-alk-1-enyl glycero-3-phosphorylcholine by hydrogenation and subsequent reaction with cadmium chloride, offers a relatively simple means of preparing a labeled saturated ether phospholipid suitable for use in metabolic studies.
topic	phosphatidalcholine 1-alkyl 3-glycero-3-phosphorylcholine-CdCl2 complex acylation saturated ether phospholipid lecithinase C hydrolysis
url	http://www.sciencedirect.com/science/article/pii/S0022227520429608
work_keys_str_mv	AT apoulos preparationoflabeledalkylacylglycerophosphorylcholine
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Preparation of labeled alkyl acyl glycerophosphorylcholine

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