Syntheses of two deacetyl-thymosin β4 analogs and their anti-inflammatory effect on carrageenin-induced edema in the mouse paw

Two {Met(0)6}deacetyl-thymosin β4 analogs containing Phe(4F) or Tyr(Me) at position 12 were synthesized by the manual solid-phase method, and their anti-inflammatory effect on carrageenin-induced edema in the mouse paw was studied. Fluorination of the para-position of Phe12 resulted in a marked anti...

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Bibliographic Details
Main Authors: T. Abiko, R. Ogawa
Format: Article
Language:English
Published: Hindawi Limited 2001-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350120054563