Precision-Cut Kidney Slices as a Tool to Understand the Dynamics of Extracellular Matrix Remodeling in Renal Fibrosis

Precision-Cut Kidney Slices as a Tool to Understand the Dynamics of Extracellular Matrix Remodeling in Renal Fibrosis

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The aim of this study was to set up an ex vivo model for renal interstitial fibrosis in order to investigate the extracellular matrix (ECM) turnover profile in the fibrotic kidney. We induced kidney fibrosis in fourteen 12-week-old male Sprague Dawley rats by unilateral ureteral obstruction (UUO) su...

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Bibliographic Details
Main Authors:	Federica Genovese, Zsolt S. Kàrpàti, Signe H. Nielsen, Morten A. Karsdal
Format:	Article
Language:	English
Published:	SAGE Publishing 2016-01-01
Series:	Biomarker Insights
Online Access:	https://doi.org/10.4137/BMI.S38439

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