In vitro/vivo assessment of praziquantel nanocrystals: Formulation, characterization, and pharmacokinetics in beagle dogs

In vitro/vivo assessment of praziquantel nanocrystals: Formulation, characterization, and pharmacokinetics in beagle dogs

To investigate the impact of particle size on in vitro/vivo performance of praziquantel (PZQ), nanocrystals (NCs) and microcrystals (MCs) of PZQ were prepared using the methods of wet milling and jet milling, respectively. PZQ NCs and MCs were characterized with dynamic light scattering, laser parti...

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Bibliographic Details
Main Authors:	Ruyi Yang, Tao Zhang, Jiang Yu, Yan Liu, Yingli Wang, Zhonggui He
Format:	Article
Language:	English
Published:	Elsevier 2019-05-01
Series:	Asian Journal of Pharmaceutical Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1818087618302381

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