The adaptor protein Swiprosin-1/EFhd2 is dispensable for platelet function in mice.

The adaptor protein Swiprosin-1/EFhd2 is dispensable for platelet function in mice.

BACKGROUND: Platelets are anuclear cell fragments derived from bone marrow megakaryocytes that safeguard vascular integrity, but may also cause pathological vessel occlusion. Reorganizations of the platelet cytoskeleton and agonist-induced intracellular Ca2+-mobilization are crucial for platelet hem...

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Bibliographic Details
Main Authors: Martina Morowski, Sebastian Brachs, Dirk Mielenz, Bernhard Nieswandt, Sebastian Dütting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4170979?pdf=render

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