Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivos⃞

Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivos⃞

Serum amyloid A (SAA) was markedly increased in the plasma and in the liver upon acute inflammation induced by intraperitoneal injection of lipopolysaccharide (LPS) in mice, and SAA in the plasma was exclusively associated with HDL. In contrast, no HDL was present in the plasma and only a small amou...

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Bibliographic Details
Main Authors: Wei Hu, Sumiko Abe-Dohmae, Maki Tsujita, Noriyuki Iwamoto, Osamu Ogikubo, Takanobu Otsuka, Yositaka Kumon, Shinji Yokoyama
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Journal of Lipid Research
Subjects:
serum amyloid A
high density lipoprotein
ATP binding cassette transporter A1
cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428597

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