Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

Being able to predict the therapeutic benefit of disease modifying anti-rheumatic drugs (DMARDs) would be of great benefit and a stepping stone towards personalized medicine. Here the authors use machine learning and lipid mediator mass spectrometry to show specialized pro-resolving mediators are in...

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Bibliographic Details
Main Authors: Esteban A. Gomez, Romain A. Colas, Patricia R. Souza, Rebecca Hands, Myles J. Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19176-z