Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography
Background: Early diagnosis of diseases is an important step in their treatment process, but it is difficult due to lack of satisfactorily sensitive imaging devices and difference in the parameters of the subjects. Asymmetry analysis of retinal nerve fiber layer thickness and total retinal thickness...
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Vesnu Publications
2013-10-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/3226 |
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doaj-f34a0af58d10460791b4831c06870fbe2020-11-25T00:44:04ZfasVesnu Publications مجله دانشکده پزشکی اصفهان1027-75951735-854X2013-10-0131247118511931392Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence TomographyTahereh Mahmudi0Raheleh Kafieh1Hossein Rabbani2Alireza Mehri Dehnavi3Mohammad Reza Akhlaghi4Khatereh Arbabian5Mohammad Ahmadi6MSc Student, Department of Bioelectric and Biomedical Engineering, School of Advanced Medical Technology AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranPhD Student, Bioelectric and Biomedical Engineering, School of Advanced Medical Technology AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, The Medical Image and Signal Processing Research Center AND Department of Bioelectric and Biomedical Engineering, School of Advanced Medical Technology, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Bioelectric and Biomedical Engineering, School of Advanced Medical Technology, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Department of Opthalmology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranGeneral Practitioner, Clinic of Diabetes, Feiz Hospital, Isfahan, IranClinic of Ophthalmology, Feiz Hospital, Isfahan, IranBackground: Early diagnosis of diseases is an important step in their treatment process, but it is difficult due to lack of satisfactorily sensitive imaging devices and difference in the parameters of the subjects. Asymmetry analysis of retinal nerve fiber layer thickness and total retinal thickness can provide a criterion for physicians to accomplish early diagnosis. Methods: Data were collected from 50 normal subjects (aged 35 ± 10 years) by a Topcon model of 3D-OCT 1000. For this purpose, a pipeline of procedures was utilized; segmentation of retinal layers by diffusion map method, scaling operator, automatic localization of the center of macula, and calculation of mean and SD. Findings: The maximum of average RNFL and total retina thickness in right and left eyes is seen in the perifoveal nasal, and the minimum is seen in the fovea. The results demonstrate an overall symmetry between the two eyes (P > 0.05). Tolerance limits in RNFL of normal subjects for 9 sectors (from 1 to 9), respectively, are 1.16 ± 0.99, 2.43 ± 1.57, 3.96 ± 2.08, 1.11 ± 1.09, 2.83 ± 1.66, 3.09 ± 1.39, 4.91 ± 1.79, 0.82 ± 1.25, and 3.31 ± 1.63 µm. Tolerance limits in total retina of normal subjects for 9 sectors, respectively, are 9.84 ± 2.75, 3.60 ± 2.74, 4.82 ± 3.23, 3.33 ± 1.76, 6.51 ± 3.69, 3.23 ± 1.30, 5.96 ± 2.62, 2.79 ± 1.42, 6.72 ± 2.57 µm. Conclusion: Asymmetry analysis can be a criterion for early detection of diseases. In this study asymmetry analysis and tolerance limits were calculated.http://jims.mui.ac.ir/index.php/jims/article/view/3226Optical coherence tomographyRetinaAsymmetry analysis |
| collection |
DOAJ |
| language |
fas |
| format |
Article |
| sources |
DOAJ |
| author |
Tahereh Mahmudi Raheleh Kafieh Hossein Rabbani Alireza Mehri Dehnavi Mohammad Reza Akhlaghi Khatereh Arbabian Mohammad Ahmadi |
| spellingShingle |
Tahereh Mahmudi Raheleh Kafieh Hossein Rabbani Alireza Mehri Dehnavi Mohammad Reza Akhlaghi Khatereh Arbabian Mohammad Ahmadi Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography مجله دانشکده پزشکی اصفهان Optical coherence tomography Retina Asymmetry analysis |
| author_facet |
Tahereh Mahmudi Raheleh Kafieh Hossein Rabbani Alireza Mehri Dehnavi Mohammad Reza Akhlaghi Khatereh Arbabian Mohammad Ahmadi |
| author_sort |
Tahereh Mahmudi |
| title |
Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography |
| title_short |
Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography |
| title_full |
Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography |
| title_fullStr |
Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography |
| title_full_unstemmed |
Evaluation of Asymmetricity of Retinal Nerve Fiber Layer and Total Retina in Right and Left Eyes of Normal Subjects Using Extracted Features from Optical Coherence Tomography |
| title_sort |
evaluation of asymmetricity of retinal nerve fiber layer and total retina in right and left eyes of normal subjects using extracted features from optical coherence tomography |
| publisher |
Vesnu Publications |
| series |
مجله دانشکده پزشکی اصفهان |
| issn |
1027-7595 1735-854X |
| publishDate |
2013-10-01 |
| description |
Background: Early diagnosis of diseases is an important step in their treatment process, but it is difficult due to lack of satisfactorily sensitive imaging devices and difference in the parameters of the subjects. Asymmetry analysis of retinal nerve fiber layer thickness and total retinal thickness can provide a criterion for physicians to accomplish early diagnosis.
Methods: Data were collected from 50 normal subjects (aged 35 ± 10 years) by a Topcon model of 3D-OCT 1000. For this purpose, a pipeline of procedures was utilized; segmentation of retinal layers by diffusion map method, scaling operator, automatic localization of the center of macula, and calculation of mean and SD.
Findings: The maximum of average RNFL and total retina thickness in right and left eyes is seen in the perifoveal nasal, and the minimum is seen in the fovea. The results demonstrate an overall symmetry between the two eyes (P > 0.05). Tolerance limits in RNFL of normal subjects for 9 sectors (from 1 to 9), respectively, are 1.16 ± 0.99, 2.43 ± 1.57, 3.96 ± 2.08, 1.11 ± 1.09, 2.83 ± 1.66, 3.09 ± 1.39, 4.91 ± 1.79, 0.82 ± 1.25, and 3.31 ± 1.63 µm. Tolerance limits in total retina of normal subjects for 9 sectors, respectively, are 9.84 ± 2.75, 3.60 ± 2.74, 4.82 ± 3.23, 3.33 ± 1.76, 6.51 ± 3.69, 3.23 ± 1.30, 5.96 ± 2.62, 2.79 ± 1.42, 6.72 ± 2.57 µm.
Conclusion: Asymmetry analysis can be a criterion for early detection of diseases. In this study asymmetry analysis and tolerance limits were calculated. |
| topic |
Optical coherence tomography Retina Asymmetry analysis |
| url |
http://jims.mui.ac.ir/index.php/jims/article/view/3226 |
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