Optimization of the Enrichment of Circulating Tumor Cells for Downstream Phenotypic Analysis in Patients with Non-Small Cell Lung Cancer Treated with Anti-PD-1 Immunotherapy

Optimization of the Enrichment of Circulating Tumor Cells for Downstream Phenotypic Analysis in Patients with Non-Small Cell Lung Cancer Treated with Anti-PD-1 Immunotherapy

The current study aimed at the optimization of circulating tumor cell (CTC) enrichment for downstream protein expression analyses in non-small cell lung cancer (NSCLC) to serve as a tool for the investigation of immune checkpoints in real time. Different enrichment approaches—ficoll density, erythro...

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Bibliographic Details
Main Authors: Maria A Papadaki, Afroditi I Sotiriou, Christina Vasilopoulou, Maria Filika, Despoina Aggouraki, Panormitis G Tsoulfas, Christina A Apostolopoulou, Konstantinos Rounis, Dimitrios Mavroudis, Sofia Agelaki
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
non-small cell lung cancer
NSCLC
immunotherapy
immune checkpoint inhibitors
ICIs
programmed cell death-1 ligand
Online Access:https://www.mdpi.com/2072-6694/12/6/1556

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