Variation in the FFAR1 gene modifies BMI, body composition and beta-cell function in overweight subjects: an exploratory analysis.

Variation in the FFAR1 gene modifies BMI, body composition and beta-cell function in overweight subjects: an exploratory analysis.

BACKGROUND:FFAR1 receptor is a long chain fatty acid G-protein coupled receptor which is expressed widely, but found in high density in the pancreas and central nervous system. It has been suggested that FFAR1 may play a role in insulin sensitivity, lipotoxicity and is associated with type 2 diabete...

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Bibliographic Details
Main Authors: Celia G Walker, Louise Goff, Les J Bluck, Bruce A Griffin, Susan A Jebb, Julie A Lovegrove, Thomas A B Sanders, Gary S Frost, RISCK Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084254?pdf=render

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