Roles of small GTPase Rac1 in the regulation of actin cytoskeleton during dengue virus infection.

Roles of small GTPase Rac1 in the regulation of actin cytoskeleton during dengue virus infection.

BACKGROUND: Increased vascular permeability is a hallmark feature in severe dengue virus (DV) infection, and dysfunction of endothelial cells has been speculated to contribute in the pathogenesis of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Rho-family GTPase Rac1 is a significant ele...

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Bibliographic Details
Main Authors:	Jia-Li Wang, Jun-Lei Zhang, Wei Chen, Xiao-Feng Xu, Na Gao, Dong-Ying Fan, Jing An
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-01-01
Series:	PLoS Neglected Tropical Diseases
Online Access:	http://europepmc.org/articles/PMC2930870?pdf=render

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