A Proposed Quantitative Index for Assessing the Potential Contribution of Reprogramming to Cancer Stem Cell Kinetics

A Proposed Quantitative Index for Assessing the Potential Contribution of Reprogramming to Cancer Stem Cell Kinetics

Enrichment of cancer stem cells (CSCs) is thought to be responsible for glioblastoma multiforme (GBM) recurrence after radiation therapy. Simulation results from our agent-based cellular automata model reveal that the enrichment of CSCs may result either from an increased symmetric self-renewal divi...

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Bibliographic Details
Main Authors:	Xuefeng Gao, J. Tyson McDonald, Mamta Naidu, Philip Hahnfeldt, Lynn Hlatky
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2014/249309

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