Immune reconstitution inflammatory syndrome associated with disseminated histoplasmosis and TNF-alpha inhibition

Endemic fungal infections are a significant problem for patients on TNF-alpha inhibitors. Immune reconstitution inflammatory syndrome, IRIS, can present in patients with waning TNF-alpha inhibition and an endemic fungal infection. There may be a potential role that TNF-alpha inhibitors can play in m...

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Bibliographic Details
Main Authors: Theodore Wright, Basak Coruh, David Fredricks, Nina Kim
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Medical Mycology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753918301404
Description
Summary:Endemic fungal infections are a significant problem for patients on TNF-alpha inhibitors. Immune reconstitution inflammatory syndrome, IRIS, can present in patients with waning TNF-alpha inhibition and an endemic fungal infection. There may be a potential role that TNF-alpha inhibitors can play in mitigating IRIS related to disseminated endemic fungal infections. Keywords: Immune reconstitution inflammatory syndrome, Histoplasmosis, TNF-alpha
ISSN:2211-7539