Minimal residual disease detection in Tunisian B-acute lymphoblastic leukemia based on immunoglobulin gene rearrangements

Minimal residual disease detection in Tunisian B-acute lymphoblastic leukemia based on immunoglobulin gene rearrangements

IGH gene rearrangement and IGK-Kde gene deletion can be used as molecular markers for the assessment of B lineage acute lymphoblastic leukemia (B-ALL). Minimal residual disease detected based on those markers is currently the most reliable prognosis factor in B-ALL. The aim of this study was to use...

Full description

Bibliographic Details
Main Authors:	S. Besbes, W.S. Hamadou, M.L. Boulland, Y.B. Youssef, B. Achour, H. Regaieg, A. Khelif, T. Fest, Z. Soua
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	IGH gene IGK gene B-ALL minimal residual disease (MRD) RQ-PCR
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000100703&lng=en&tlng=en

Similar Items

A Proposed New Nomenclature for the Immunoglobulin Genes of Mus musculus
by: Christian E. Busse, et al.
Published: (2019-12-01)

Enhancing B-Cell Malignancies—On Repurposing Enhancer Activity towards Cancer
by: Marta Elżbieta Kasprzyk, et al.
Published: (2021-06-01)

Detection of tumor-specific marker for minimal residual disease in multiple myeloma patients
by: Lenka Sedlarikova, et al.
Published: (2015-12-01)

The Combination of Rituximab and Bendamustine as First-Line Treatment Is Highly Effective in the Eradicating Minimal Residual Disease in Follicular Lymphoma: An Italian Retrospective Study
by: Sara Galimberti, et al.
Published: (2017-06-01)

Monoclonal immunoglobulin heavy chain gene rearrangement in Fuchs’ uveitis
by: Hisae Nakahara, et al.
Published: (2018-03-01)

Immunoglobulin genes and T-cell receptors as molecular markers in children with acute lymphoblastic leukaemia
by: Lazić Jelena, et al.
Published: (2009-01-01)

Immunoglobulin heavy chain gene rearrangements in patients with Gaucher disease
by: Rodić Predrag, et al.
Published: (2018-01-01)

VH Replacement Footprint Analyser-I (VHRFA-I), a Java based Computer Program for Analyses of Immunoglobulin Heavy Chain Genes and Potential VH Replacement Products in Human and Mouse
by: Lin eHuang, et al.
Published: (2014-02-01)

AVALIAÇÃO DE DOENÇA RESIDUAL MÍNIMA EM PACIENTES COM LEUCEMIA MIELÓIDE CRÔNICA.
by: Leal, Caio Bruno Quinta de Souza
Published: (2016)

IMPre: an accurate and efficient software for prediction of T- and B-cell receptor germline genes and alleles from rearranged repertoire data
by: Wei Zhang, et al.
Published: (2016-11-01)

Minimal Residual Disease in Acute Lymphoblastic Leukemia: Technical and Clinical Advances
by: Irene Della Starza, et al.
Published: (2019-08-01)

Anknytningsstil och ledarskap
by: Larsson, Monika
Published: (2016)

Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires
by: Yang Yang, et al.
Published: (2015-09-01)

Silencing immunoglobulin gene enhancers as a potential treatment strategy for multiple myeloma
by: Toman, Inka
Published: (2009)

Characterization of DNA G-Quadruplex Structures in Human Immunoglobulin Heavy Variable (IGHV) Genes
by: Catherine Tang, et al.
Published: (2021-05-01)

MRD-Nets: Multi-Scale Residual Networks With Dilated Convolutions for Classification and Clustering Analysis of Spacecraft Electrical Signal
by: Yixin Liu, et al.
Published: (2019-01-01)

The complex translocation (9;14;14) involving IGH and CEBPE genes suggests a new subgroup in B-lineage acute lymphoblastic leukemia
by: Rachid Zerrouki, et al.
Published: (2016-03-01)

Immunophenotypic Modulation of the Blast Cells in Childhood Acute Lymphoblastic Leukemia Minimal Residual Disease Detection
by: Burnusuzov Hasan A., et al.
Published: (2016-03-01)

Investigating the Correlation Between TGF-β Gene Expression and Disease-Related Prognostic Factors in Bone Marrow Aspiration of Adults With Acute Lymphoblastic Leukemia
by: Amin Mirzaeian, et al.
Published: (2019-01-01)

FAMLF is a target of miR-181b in Burkitt lymphoma
by: J.G. Li, et al.

The Role of Monitoring the Bcr-Abl Transcript Levels in the Management of Patients with Chronic Myeloid Leukemia
by: Tunyogi Aliz-Beáta, et al.
Published: (2013-04-01)

Day 15 and Day 33 Minimal Residual Disease Assessment for Acute Lymphoblastic Leukemia Patients Treated According to the BFM ALL IC 2009 Protocol: Single-Center Experience of 133 Cases
by: Letitia-Elena Radu, et al.
Published: (2020-06-01)

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation
by: Charlotte Proudhon, et al.
Published: (2016-06-01)

Editorial: Overlapping Phenotypes and Genetic Heterogeneity of Rare Neurodevelopmental Disorders
by: Francesca Cogliati, et al.
Published: (2021-07-01)

Modulation of the 3'IgH Regulatory Region (3'IgH RR), a prospective in vitro screening tool for identifying potential immunotoxicants
by: Henseler, Rebecca Anne
Published: (2007)

Testing for minimal residual disease in adults with acute lymphoblastic leukemia in Europe: a clinician survey
by: Arnaud Pigneux, et al.
Published: (2018-11-01)

Clonality testing of lymphoproliferative disorders in a large cohort of primary and consultant biopsies
by: Michaela Svachova, et al.
Published: (2017-06-01)

MRD Tailored Therapy in AML: What We Have Learned So Far
by: Lok Lam Ngai, et al.
Published: (2021-01-01)

Early vs. late MRD response- and risk-based treatment intensification of childhood acute lymphoblastic leukemia: a prospective pilot study from Saudi Arabia
by: Wasil Jastaniah, et al.
Published: (2018-11-01)

ETV6/RUNX1-positive childhood acute lymphoblastic leukemia in China: excellent prognosis with improved BFM protocol
by: Yu Wang, et al.
Published: (2018-08-01)

Proposal for the standardization of ﬂow cytometry protocols to detect minimal residual disease in acute lymphoblastic leukemia
by: Maura Rosane Valério Ikoma, et al.
Published: (2015-12-01)

Clinical implications of transforming growth factor-beta–induced gene-h3 protein expression in lung cancer
by: He CJ, et al.
Published: (2016-08-01)

Mouse Models of c-myc Deregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis
by: Melissa Ferrad, et al.
Published: (2020-07-01)

Prognostic value of 13q14 deletion and IgH 14q32 rearrangement by interphase fluorescence in situ hybridization in patients with multiple myeloma
by: Nevine A Kassem, et al.
Published: (2014-01-01)

Down-Regulated FOXO1 in Refractory/Relapse Childhood B-Cell Acute Lymphoblastic Leukemia
by: Qingqing Zheng, et al.
Published: (2020-11-01)

Post-Transplant Maintenance Therapy for Patients with Acute Myeloid Leukemia: Current Approaches and the Need for More Trials
by: Assi R, et al.
Published: (2021-01-01)

Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia
by: E. Genescà, et al.
Published: (2018-07-01)

No prognostic significance of normalized copy number of PML-RARA transcript at diagnosis in patients with acute promyelocytic leukemia
by: Eman O. Rasekh, et al.
Published: (2021-06-01)

Detection and therapy of neuroblastoma minimal residual disease using [64/67Cu]Cu-SARTATE in a preclinical model of hepatic metastases
by: Jason L. J. Dearling, et al.
Published: (2021-02-01)

Corrigendum: Down-Regulated FOXO1 in Refractory/Relapse Childhood B-Cell Acute Lymphoblastic Leukemia
by: Qingqing Zheng, et al.
Published: (2020-12-01)