Binding characterization of the targeting drug AIMPILA to AFP receptors in human tumor xenografts

The main objective of this study was the characterization of preclinical tumor models based on their expression of alpha-fetoprotein receptor (RECAF) for targeting cancer cells with a new non-covalent complex (AIMPILA) containing alpha-fetoprotein as the carrier and Atractyloside as an apoptosis-ind...

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Bibliographic Details
Main Authors: Janneta Tcherkassova, Sergei Tsurkan, Galina Smirnova, Julia Borisova, Ricardo Moro, Helen Treshalina
Format: Article
Language:English
Published: IOS Press 2017-10-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317734815