Age-related transcriptional modules and TF-miRNA-mRNA interactions in neonatal and infant human thymus.

Age-related transcriptional modules and TF-miRNA-mRNA interactions in neonatal and infant human thymus.

The human thymus suffers a transient neonatal involution, recovers and then starts a process of decline between the 1st and 2nd years of life. Age-related morphological changes in thymus were extensively investigated, but the genomic mechanisms underlying this process remain largely unknown. Through...

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Bibliographic Details
Main Authors: Fernanda Bernardi Bertonha, Silvia Yumi Bando, Leandro Rodrigues Ferreira, Paulo Chaccur, Christiana Vinhas, Maria Claudia Nogueira Zerbini, Magda Maria Carneiro-Sampaio, Carlos Alberto Moreira-Filho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227547

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https://doi.org/10.1371/journal.pone.0227547

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