RNA sequencing demonstrates large-scale temporal dysregulation of gene expression in stimulated macrophages derived from MHC-defined chicken haplotypes.

Discovering genetic biomarkers associated with disease resistance and enhanced immunity is critical to developing advanced strategies for controlling viral and bacterial infections in different species. Macrophages, important cells of innate immunity, are directly involved in cellular interactions w...

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Bibliographic Details
Main Authors: Kristopher J L Irizarry, Eileen Downs, Randall Bryden, Jory Clark, Lisa Griggs, Renee Kopulos, Cynthia M Boettger, Thomas J Carr, Calvin L Keeler, Ellen Collisson, Yvonne Drechsler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5573159?pdf=render