Assessment and prediction of tablet properties using transmission and backscattering Raman spectroscopy and transmission NIR spectroscopy

Assessment and prediction of tablet properties using transmission and backscattering Raman spectroscopy and transmission NIR spectroscopy

This study investigated whether Raman and Near Infrared (NIR) spectroscopy could predict tablet properties. Granules were produced on a continuous line by varying granulation parameters. Tableting process parameters were adjusted to obtain uniform tablet weight and thickness. Spectra were collected...

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Bibliographic Details
Main Authors: Elisabeth Peeters, Ana Filipa Tavares da Silva, Maunu Toiviainen, Jeroen Van Renterghem, Jurgen Vercruysse, Mikko Juuti, Joao Almeida Lopes, Thomas De Beer, Chris Vervaet, Jean-Paul Remon
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Continuous production
PAT
Granulation
Tableting
NIR
Raman
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616300290

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