lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM1

lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM1

In this study, we examined the clinical significance and molecular mechanisms of a long non-coding RNA (lncRNA), double homeobox A pseudogene 8 (DUXAP8) in hepatocellular carcinoma (HCC). DUXAP8 expression was compared using quantitative real-time PCR in HCC versus adjacent tissues and in HCC cell l...

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Bibliographic Details
Main Authors: Yu Hu, Xian Zhang, Hong-Yan Zai, Wei Jiang, Liang Xiao, Qin Zhu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Oncolytics
Subjects:
hepatocellular carcinoma
DUXAP8
miR-485-5p
FOXM1
PARP inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301613

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