Aggressive immunosuppressive treatment of Susac's syndrome in an adolescent: using treatment of dermatomyositis as a model

<p>Abstract</p> <p>We describe aggressive immunosuppressive treatment of an adolescent with Susac's syndrome (SS), a disease of the microvasculature in the brain, retina, and inner ear. Because the immunopathogenesis of SS appears to have much in common with that of juvenile d...

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Bibliographic Details
Main Authors: Grzybowski Deborah M, Martin Lisa, Rusin Jerome, Lubow Martin, Rennebohm Robert M, Susac John O
Format: Article
Language:English
Published: BMC 2008-01-01
Series:Pediatric Rheumatology Online Journal
Online Access:http://www.ped-rheum.com/content/6/1/3
Description
Summary:<p>Abstract</p> <p>We describe aggressive immunosuppressive treatment of an adolescent with Susac's syndrome (SS), a disease of the microvasculature in the brain, retina, and inner ear. Because the immunopathogenesis of SS appears to have much in common with that of juvenile dermatomyositis (JDM), the patient was treated with an approach that has been effective for severe JDM. The patient's outcome provides evidence for the importance of prompt, aggressive, and sustained immunosuppressive treatment of encephalopathic SS.</p>
ISSN:1546-0096