Combination of Gemcitabine with Cell-Penetrating Peptides: A Pharmacokinetic Approach Using In Silico Tools

Combination of Gemcitabine with Cell-Penetrating Peptides: A Pharmacokinetic Approach Using In Silico Tools

<b> </b>Gemcitabine is an anticancer drug used to treat a wide range of solid tumors and is a first line treatment for pancreatic cancer. Our group has previously developed novel conjugates of gemcitabine with cell-penetrating peptides (CPP), and here we report some preliminary data rega...

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Bibliographic Details
Main Authors: Abigail Ferreira, Rui Lapa, Nuno Vale
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
gemcitabine
cell-penetrating peptides (cpp)
in silico
pharmacokinetics
gastroplus™
z-scale
Online Access:https://www.mdpi.com/2218-273X/9/11/693

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https://www.mdpi.com/2218-273X/9/11/693

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