Allosteric mechanism of the V. vulnificus adenine riboswitch resolved by four-dimensional chemical mapping

The structural interconversions that mediate the gene regulatory functions of RNA molecules may be different from classic models of allostery, but the relevant structural correlations have remained elusive in even intensively studied systems. Here, we present a four-dimensional expansion of chemical...

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Bibliographic Details
Main Authors: Siqi Tian, Wipapat Kladwang, Rhiju Das
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/29602